ptXPRO is a maximum dose pterostilbene supplement. Pterostilbene is a powerful, bioavailable antioxidant found in blueberries. Pterostilbene activates a unique class of enzymes called sirtuin enzymes, which help to support healthy aging by regulating gene expression, mitochondrial function and energy metabolism, thus addressing cellular damage. These functions keep cells healthy.* A healthy life requires healthy cells. ptXPRO is a true anti-aging supplement which keeps your cells healthy and supports their metabolic function – Lifespan Extension, Metabolic Health and Anti-Aging. Take ptXPRO for maximizing your health span – the length of your life that is when you are healthy.*
ptXPRO is a maximum dose anti-aging formula. It is proudly manufactured in the USA and sold exclusively in the USA. It contains extremely high quality pterostilbene – under the exclusive brand name of pteroGEN®. Every batch is third-party tested to ensure professional-grade quality and purity. And unlike other pterostilbene products, ptXPRO features only high-quality top-manufacturer delayed-release vegan (non-gelatin) capsules which are clinically proven to resist stomach acids for targeted absorption in the small intestine – this means it’s made available to be absorbed in the colon - where it’s best utilized. Our outer packaging includes BPA free ultraviolet glass for superior preservation, as well as FSC mix box material and soy-based inks to help protect forests and promote sustainable practices in the packaging industry.
The science of healthy aging is clear: Cell health = Your health.
* FDA has not evaluated these product claims. This dietary supplement is not intended to diagnose, treat, cure, or prevent any disease
Take one (1) capsule daily, without food in the morning, or as directed by your healthcare professional. Consult your healthcare professional before taking any dietary supplement, if you are pregnant, nursing, or taking any medication. Keep out of reach of children.
Store in a cool, dry place away from direct sunlight. Do not use if tamper-evident packaging is broken or missing.
Pterostilbene: A Potent Natural Compound for Anti-aging, Cellular and Metabolic Health and Long Healthspan*
Pterostilbene is a naturally occurring polyphenolic compound found in blueberries, grapes and some medicinal plants. (1-4) Pterostilbene contains two methoxy groups and one hydroxyl group. (3) This structural uniqueness contributes to its enhanced lipophilicity (fat solubility), fast membrane permeability, and enhanced bioavailability. (3) It has garnered significant attention in recent years, owing to its health benefits and therapeutic applications. This review summarizes the current understanding of the biological functions, pharmacological properties, and health benefits of pterostilbene.
Biological Functions and Mechanisms*
Pterostilbene has a wide range of biological functions, including being a powerful antioxidant with anti-inflammatory, cellular protective, and neuroprotective properties. (5, 2, 6) Its primary mechanism of action involves the modulation of multiple signaling pathways related to oxidative stress, inflammation, and cellular senescence. (7, 8)
Antioxidant Properties*
Oxidative stress in the body is caused by a disturbance in the balance between the production of reactive oxygen species (ROS) in the cell, and the cell’s ability to detoxify these molecules. Antioxidants are necessary to maintain the critical equilibrium between ROS production and scavenging. ROS accumulation can result in damaged mitochondrial DNA and protein. Strong protection against oxidative stress is critical to health, wellness and vitality. Pterostilbene is a highly bioavailable antioxidant. with profound detoxifying properties. (2)
Sirtuin Signaling Properties*
Pterostilbene activates a unique class of enzymes called sirtuin enzymes, which help to support healthy aging by regulating gene expression, mitochondrial function and energy metabolism, thus addressing cellular damage. Sirtuins are a family of seven signaling proteins (SIRT1-7) that act as nicotinamide adenine dinucleotide (NAD+)-dependent deacetylases and ADP-ribosyltransferases. (9, 10) Sirtuins are found in nearly all living organisms. They are distributed throughout mammalian cells, primarily in the nucleus (SIRT1, 6, 7), cytoplasm (SIRT1, 2), and mitochondria (SIRT3, 4, 5). These are "guardian" enzymes that regulate metabolic homeostasis, repair damaged DNA, reduce inflammation, and enhance mitochondrial function. Because they require NAD+ —a molecule linked to nutritional status—sirtuins function as energy sensors, linking nutrient availability to gene expression and cellular lifespan.
The sirtuin family of 7 enzymes have the following functions:
SIRT1: Metabolism, inflammation, lifespan.
SIRT2: Mitosis, cell cycle regulation.
SIRT3: Mitochondrial energy metabolism.
SIRT4: Glutamine metabolism and insulin regulation.
SIRT5: Urea cycle regulation.
SIRT6: DNA repair, genomic stability, glucose metabolism.
SIRT7: rDNA transcription and cellular health.
Sirtuin plays an essential role in Health and Aging in three areas:
Lifespan Extension: Sirtuins control aging by enabling stress resistance.
Metabolic Health: Dysregulation of sirtuins is linked to metabolic syndrome, glucose control, and fatty liver.
Age-Related Health: Sirtuins regulate DNA repair and inflammation.
Health Benefits*
Pterostilbene has been shown to be beneficial for a broad spectrum of health conditions, including cellular health, (12,13) cardiovascular health, (2,14,15) liver health, (16-18) glucose control, (18-19) neuroprotection, (6,14) and mitochondrial health. (21) These benefits contribute to healthy aging.
Healthy Aging*
This is where pterostilbene truly shines. Pterostilbene has been shown to modulate various hallmarks of aging, including oxidative damage, inflammation, telomere attrition, and cell senescence. (8) The sirtuin enzymes as discussed above promote cellular and metabolic health, longevity and healthy aging. This makes pterostilbene, a one-of-a-kind molecule naturally found in blueberries, the molecule to take to enhance your healthspan.
Safety
Pterostilbene is naturally found in blueberries and other fruits and berries. It is safe for use in humans, with no adverse drug reactions to hepatic, renal, or glucose markers. (22)
*This literature review has not been evaluated by the Food and Drug Administration, and therefore the information contained herein is not intended to diagnose, treat, cure, or prevent any disease.
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