Every organ, muscle and tissue in your body is made of cells. A healthy cell divides and replicates until it reaches cellular senescence, at which point it can no longer divide, and the cell dies. The aging of your body tracks alongside this lifecycle of your cells. Typically, your chronological age will match the biological age of your cells. However, with the right supplementation, in conjunction with proper health and lifestyle habits, it is possible to have much healthier—i.e. biologically younger—cells than your chronological age. 

Cell health = Your health!

Nicotinamide riboside (NR) is a form of vitamin B3 (niacin) and is a precursor to nicotinamide adenine dinucleotide (NAD+). NAD+ is a critical coenzyme found in every cell of your body and plays a significant role in energy production, DNA repair, and various other cellular processes. Declining NAD+ levels have been associated with aging and several age-related diseases. Several studies have explored the effects of NR supplementation, with findings suggesting potential benefits related to metabolic health, protection against neurodegenerative diseases, and improved muscle function.

Oral NAD+ supplements have low bioavailability because NAD+ is a large, charged molecule that doesn’t easily cross cell membranes, and is unstable in the digestive tract.  As a precursor to NAD+, NR has better bioavailability, as it is smaller, more stable, and directly enters the NAD+ salvage pathway after absorption. 

Oxidative stress is a phenomenon in the body caused by a disturbance in the balance between the production of reactive oxygen species (ROS) in the cell, and the cell’s ability to detoxify these products. Healthy cells require the correct balance between ROS and antioxidants, as ROS accumulation can result in damaged mitochondrial DNA and protein. Antioxidants are the frontline warriors in the fight to maintain equilibrium between ROS production and scavenging, also known as mitochondrial redox (oxidation reduction) homeostasis. Simply put, sufficient antioxidants are critical to cellular health. 

Extracted compounds are directly isolated from plants through methods like distillation, solvent extraction, or cold pressing. Many extracts come from China and may contain harmful chemicals, allergens, toxins, or variable levels of active ingredients, which could pose risks if not properly tested. Finally, variability in plant material, growing conditions, and extraction methods can cause inconsistencies in potency, while overharvesting, deforestation, and improper farming practices can lead to ecological damage and biodiversity loss.

Compounds synthesized in a laboratory precisely replicate the structure of plant compounds while improving stability, consistency and potency. These structures are controlled and typically much purer because they are isolated. Finally, this process is more sustainable and less taxing on the environment because it does not require vast amounts of plant material.

No! Supplements are NOT created equally. The supplement industry in America is essentially unregulated, and countless products are manufactured overseas in questionable facilities. It is critically important to both study the Supplement Facts on any label, as well as confirm the product was manufactured in a facility that is registered with the FDA as a “GMP” which stands for “Good Manufacturing Practices”. Third-party testing is also necessary to show whether a product contains heavy metals or any other unwanted contaminants. 

It is generally safe and encouraged to take our products in combination, however we recommend consulting with your healthcare professional before starting any dietary supplement regimen, if you are pregnant, nursing, or taking any medication.

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